Wednesday, August 15, 2012

ETIOLOGY & TREATMENT FOR SEBORRHEIC DERMATITIS


The etiology of seborrheic dermatitis is undetermined. That it is in­fluenced by the relative amounts of androgens and estrogens in the body seems clear. Investigations have confirmed the presence of a lipophylic, pleomorphic fungus, called the Pityrosporum ovale, in profuse numbers in most of the scalp lesions. This fungus is accepted by some as the cause of the disease, and by others is regarded as a saprophyte thriving in the favorable growth conditions provided by the seborrheic skin. Other in­vestigators have demonstrated that the P. ovale is abundantly present on the scalps of patients who have no clinical signs of the disease.

Many patients with the disease have low basal metabolic rates, and eat excessively of sweets, starches, or fats. Alcoholic drinks, chocolate or large amounts of cream, butter, milk, or sweets are harmful. Apparently there is a deficiency of vitamin B in some cases. Probably some of the various
expressions or seborrheic dermatitis are due to different causes, including the staphylococcus and streptococcus which are numerous in the crusts, and cause concurrent staphylococcic folliculitis and Staphylococcic ec/ematoid dermatitis. In some instances the disease seems to be mildly infectious, but is not regularly SO. It is made worse by conditions that increase per­spiration or sebaceous activity. Some cases bear such a close clinical resem­blance to psoriasis that there is some justification in thinking their etiologies must be similar.

The pathologic findings are those of a low grade- inflammatory process,
In the epidermis there are Spotty parakeratosis, acanthosis and spongiosis and occasional vesicle formation. In the corinin the subpapillary vessels are dilated, and there is a moderate! perivascular infiltration with lymphocytes. These changes all vary considerably in different grades of the condition, being more pronounced in the acute and psoriasiform types. It is differen­tiated from psoriasis by the spongiosis and vesicle formation, but often cannot be differentiated from eczema or other low grade inflammations.

Treatment. The scalp usually should be shampooed once a week, or if excessively oily, twice a week. Selenium sulfide shampoo suspension (Abbott) gives excellent results but tends to make the hair oily if used too frequently. For very oily scalps tincture saponis viridis or a 5 per cent solution of sodium lauryl sulfate (U.S.P.) are better. Sebezon lotion con­taining 10 per cent sodium sulfacetamide (Sehering) is extremely effective both   on   the seal])  and  skin.   It   is  applied   morning  and  night.

The following drugs are commonly incorporated in scalp lotions and pomades. Considerable caution must be exercised to obtain good phar­maceutical preparations which will cllect (he desired clinical results. Hesorcin or betanaphthol should not be used on blond or white hair, and mercury and sulfur should only be combined in the same prescription if the red or yellow oxides ol mercury are used. Sulfur or ainmoniated mercury are effective antiseptics but should never be used in the same prescription. A moderate amount of alcohol in scalp lotions is definitely antiseptic and there is no objection to its use. Any diving action from it may be avoided by the addition of oil to the lotion, castor oil being usually incorporated in small amounts in lotions to be used by men. Oils in seal]) lotions for women are to be avoided because they tend to make the hair stringy. When oils are. used for women they are best applied only immediately before shampooing but, if necessary, may be used more often in the form of brilliantines.

Effective prescriptions for the treatment  of the scalp are as follows:
R     Resorcinol............................................................................. 4.0-15.0
Rctanaphtliol    ........................................................................        2.0
Alcohol   .................................................................................    120.0
Distilled water............................................................... q.S. ad 240.0
Oil of violet or oil of bay.........................................................        0.24
Tincture cudbear  ....................................................................        0.5
M. and S. For dark hair only. Violet color and odor for women. Hay odor and brown :olor for men. Apply above lotion daily.
R     Dilute sulfurous acid   .............................................................      15.0
Alcohol   .................................................................................    120.0
Acetone   ................................................................................       15,0
Distilled water............................................................... q.S. ad 240.0
M. and S. Very drying antiseptic lotion for excessively oily scalp and hair.
R     Tincture capsicum   .................................................................      4.00
Chloral hydrate........................................................................      8.00
Alcohol   ................................................................................     120.0
Oil violet or oil ncroli...............................................................      0.21
Distilled water................................................................ qs. ad     210.0
M. and S. Apply to scalp daily with cotton (or dropper or toothbrush) and massage in, as directed, for three minutes.
Mercury may be substituted in similar prescriptions:
R    Mercury bichloride  .............................................................. 0.12-0.24
Resorcinol   .......................................................................... 4.0-15.0
Spt. formic acid  ......................................................................      15.0
Alcohol.....................................................................................      60.0
Distilled water................................................................ q.s. ad 210.0
M. and S. Apply to scalp daily with dropper and massage in as directed. For use only when hair is dark.
R     Sol. coal tar..............................................................................        8.0
Mercury bichloride..................................................................        0.24
Alcohol   ....................................................................... q.s. ad  240.0
.VI. and S, For oily hair. Apply daily with cotton,


2 comments:

  1. Try cure herbals skin care products for different kinds of skin disease treatment.

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